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Crohn’s disease:Innate immunodeficiency?
作者单位:Gastro-intestinal Unit and Center for the Study of Inflammatory Bowel Disease Massachusetts General Hospital and Harvard Medical School Boston MA 02114 United States,Gastro-intestinal Unit and Center for the Study of Inflammatory Bowel Disease Massachusetts General Hospital and Harvard Medical School Boston MA 02114 United States
摘    要:
iNtRODuCtiON Over a period of many years Crohn’s Disease (CD) has been thought to result predominantly from excessive activation of type 1 helper T cells (TH1) with a characteristic cytokine profile including elevated interferon-γ and IL-2. However the …

关 键 词:Crohn’s disease  Innate immunity  Immuno- deficiency  NOD2
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