Crohn’s disease:Innate immunodeficiency? |
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作者单位: | Gastro-intestinal Unit and Center for the Study of Inflammatory Bowel Disease Massachusetts General Hospital and Harvard Medical School Boston MA 02114 United States,Gastro-intestinal Unit and Center for the Study of Inflammatory Bowel Disease Massachusetts General Hospital and Harvard Medical School Boston MA 02114 United States |
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摘 要: | iNtRODuCtiON Over a period of many years Crohn’s Disease (CD) has been thought to result predominantly from excessive activation of type 1 helper T cells (TH1) with a characteristic cytokine profile including elevated interferon-γ and IL-2. However the …
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关 键 词: | Crohn’s disease Innate immunity Immuno- deficiency NOD2 |
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