| 银屑净提取工艺的优化 |
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| 引用本文： | 张浚,邓朝晖,徐月红,陈志良.银屑净提取工艺的优化[J].中国药师,2014(5):760-763. |
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| 作者姓名： | 张浚 邓朝晖 徐月红 陈志良 |
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| 作者单位： | 南方医科大学南方医院药学部 广州 510515； 广州军区联勤部药品仪器检验所；;广州军区联勤部药品仪器检验所；;中山大学药学院;南方医科大学南方医院药学部 |
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| 摘 要： | 优选银屑净的最佳提取工艺。方法：采用正交试验法，选择回流时间、回流次数、乙醇浓度、乙醇用量为考察因素，以大黄素、蛇床子素含量为评价指标，进行银屑净的工艺优化。结果：最佳提取工艺为8倍药材量的80％浓度乙醇回流2次，每次2h。结论：优选工艺稳定可行，可作为实际生产工艺。
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| 关 键 词： | 银屑净 工艺优化 正交试验法 方差分析 |
| 收稿时间： | 2013/12/25 0:00:00 |
| 修稿时间： | 2014/2/11 0:00:00 |
Optimization of Extraction Process for Yinxiejing |
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| Zhang Jun,Deng Zhaohui,Xu Yuehong and Chen Zhiliang.Optimization of Extraction Process for Yinxiejing[J].China Pharmacist,2014(5):760-763. |
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| Authors: | Zhang Jun Deng Zhaohui Xu Yuehong and Chen Zhiliang |
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| Institution: | Zhang Jun,Deng Zhanghui,Xu Yuehong, Chen Zhiliang (1. Department of Pharmaceutical Sciences, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China; 2. The Institute for Drug and Instrument Control of Guangzhou Military Region; 3. School of Pharmaceutical Sciences, Sun y.at-sen University) |
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| Abstract: | ABSTRACT Objective: To study the optimal extraction process of Yinxiejing. Methods: An orthogonal experimental method was used with reflux time, reflux times, ethanol concentration and volume as the influencing factors, and emodin and osthole content as the indices.Results:The optimal extraction conditions for Yinxiejing were as follows: refluxing twice with 2 h every time using 8 fold 80% ethanol. Conclusion:The optimum process is stable and feasible. |
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| Keywords: | Yinxiejing Process optimization Orthogonal experimen Variance analysis |
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