| Chinese-made electrolytic detachable coil in the embolization of a dog aneurysmal model |
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| 作者姓名： | 杨新健 吴中学 王忠诚 李佑祥 刘作勤 唐军 孙异临 张友平 尹可 |
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| 作者单位： | Beijing Neurosurgical Institute!Beijing100050，China，Beijing Neurosurgical Institute!Beijing100050，China，Beijing Neurosurgical Institute!Beijing100050，China，Beijing Neurosurgical Institute!Beijing100050，China，Shandong MedicalImage Institute!Shandong320057 |
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| 基金项目： | TheresearchwassupportedbytheNationalProgramforKey
ScienceandTechnologyProject，the 9thFive YearPlan (No .96 90 7
0 2 0 2 ) |
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| 摘 要： | Objective To develop a Chinese-made electrolytic detachable coil (CEDC) that would allow patients to enjoy the benefit of electrolytic detachable coil without having to rely on the expensive Guglielmi detachable coil (GDC)， and to test the safety and efficiency of CEDC. Methods Radiopacity of the marker of the CEDC was tested. The anti-strain force of coils and connection points were measured. In vitro and in vivo electrolyses were conducted. We produced 21 aneurysm models including lateral， bifurcation， and terminal aneurysm models， and embolized 18 models with CEDC. Results Radiopacity of the marker was satisfactory. Anti-strain of the coil and the connection point have shown the safety and efficiency of CEDC. Electrolysis in vitro and vivo, was similar to that of GDC. 83% of the aneurysm models were completely occluded. Coils were found to induce thrombosis in the aneurysm cavity, and could lead to a new endothelium over the entrance of the aneurysm, with organized tissue replacing thrombosis in 2 months. Conclusions CEDC is as efficient and safe as GDC. The marker， the ability to induce thrombosis inside the sac and the growth of new endothelium over the orifice are very satisfactory.
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| 关 键 词： | aneurysms · electrolytic detachable coils |
Chinese-made electrolytic detachable coil in the embolization of a dog aneurysmal model |
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| YANG Xinjian,WU Zhongxue,WANG Chungcheng.Chinese-made electrolytic detachable coil in the embolization of a dog aneurysmal model[J].Chinese Medical Journal,2000,113(10):921-926. |
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| Authors: | YANG Xinjian WU Zhongxue WANG Chungcheng |
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| Institution: | Beijing Neurosurgical Institute, Beijing 100050, China;Beijing Neurosurgical Institute, Beijing 100050, China;Beijing Neurosurgical Institute, Beijing 100050, China;Beijing Neurosurgical Institute, Beijing 100050, China;Shandong Medical Image Institute, Shandong 320057, China;Shandong Medical Image Institute, Shandong 320057, China;Beijing Neurosurgical Institute, Beijing 100050, China;Beijing Neurosurgical Institute, Beijing 100050, China;Beijing Neurosurgical Institute, Beijing 100050, China |
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| Abstract: | Obejctive To develop a Chinese-made electrolytic detachable coil (CEDC) that would allow patients to enjoy the benefit of electrolytic detachable coil without having to rely on the expensive Guglielmi detachable coil (GDC), and to test the safety and efficiency of CEDC Methods Radiopacity of the marker of the CEDC was tested The anti strain force of coils and connection points were measured In vitro and in vivo electrolyses were conducted We produced 21 aneurysm models including lateral, bifurcation, and terminal aneurysm models, and embolized 18 models with CEDC Results Radiopacity of the marker was satisfactory Anti strain of the coil and the connection point have shown the safety and efficiency of CEDC Electrolysis in vitro and vivo, was similar to that of GDC 83% of the aneurysm models were completely occluded Coils were found to induce thrombosis in the aneurysm cavity, and could lead to a new endothelium over the entrance of the aneurysm, with organized tissue replacing thrombosis in 2 months Conclusions CEDC is as efficient and safe as GDC The marker, the ability to induce thrombosis inside the sac and the growth of new endothelium over the orifice are very satisfactory |
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| Keywords: | ,electrolytic detachable coils |
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