Dihydro-5,6-imidazo[2,1-b]thiazoles, dihydro-2,3-imidazo[2,1-b]benzothiazoles, analogs of levamisole |
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| Authors: | H Amarouch P R Loiseau M Bonnafous R Caujolle M Payard P M Loiseau C Bories P Gayral |
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| Affiliation: | Département de Chimie Pharmaceutique, Faculté de Pharmacie, Toulouse, France. |
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| Abstract: | ![]()
New compounds containing 5,6-dihydro imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro imidazo[2,1-b]thiazole and 2,3-dihydro imidazo[2,1-b]benzothiazole rings, substituted by heterocycles analogue to chromones, were synthesized and screened against three nematodes, in vitro. The results indicate moderate anthelmintic properties, compared to levamisole; nevertheless, some products exhibit a significant degree of activity. |
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