进展性脑梗死相关因素临床分析

目的探讨影响进展性脑梗死的相关危险因素。方法回顾性总结2008年3月至2011年3月本院收治的48h内进展性脑梗死患者36例,随机抽取诊断明确的非进展性性脑梗死42例,观察项目包括体温、血压,采血检测白细胞、血糖、胆固醇、甘油三酯、颈动脉是否狭窄,颈动脉斑块程度。然后进行统计学分析。结果进展性脑梗死组中合并发热、白细胞增高、颈内动脉狭窄、颈动脉斑块例数显著增多,与对照组比较差异具有统计学意义（P〈0.05）。空腹血糖、胆固醇、甘油三酯及收缩压变化与对照组比较差异有统计学意义（P〈0.05）。两组舒张压比较,差异无统计学意义（P〉0.05）。结论脑梗死患者出现发热、白细胞增高,空腹血糖、胆固醇、甘油三酯升高,颈动脉狭窄和斑块形成,是进展性脑梗死的相关因素。

Study of related factors of progressive cerebral infarction

Objective To analyze the relative factors that caused progressive cerebral infarction（PCI）. Methods We selected 36 cases of progressive cerebral infarction patients within 48 hours of onset from march 2008 to march 2010 in our hospital. 42 cases were diagnosed as non progressive cerebral infarction.Observation items included body temperature, blood pressure,white blood cell, blood glucose, cholesterol, triglycerides, carotid artery stenosis, carotid artery plague. Then statistical analysis was carried on. Results The comparison between the control group and the progressive cerebral infarction group which combined fever, elevated white blood cell, the internal carotid artery stenosis and the obviously increased carotid artery plaque was statistically significant（P0.05）. The comparison between the control group and the changes of fasting blood glucose, cholesterol, triglycerides and systolic blood pressure was statistically significant（P〉0.05）. The comparison between the two groups of diastolic blood pressure was not statistically significant. Conclusion Fever, increase of white blood cells, elevation of fasting blood glucose, cholesterol and triglycerides, carotid stenosis and plaque formation are the risk factors that caused progressive cerebral infarction （PCI）.