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EEG abnormalities in bipolar affective disorder
Authors:B L Cook  S Shukla  A L Hoff
Affiliation:1. Developmental Imaging and Psychopathology lab, Department of Psychiatry, School of Medicine, University of Geneva, Geneva, Switzerland;2. Center for Contextual Psychiatry, Department of Neuroscience, KU Leuven, Leuven, Belgium;3. Child and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Children Hospital Bambino Gesù, Rome, Italy;4. Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany;5. Developmental Clinical Psychology Unit, Faculty of Psychology, University of Geneva, Switzerland;6. Research Department of Clinical, Educational and Health Psychology, University College London, UK;7. Department of Genetic Medicine and Development, School of Medicine, University of Geneva, Geneva, Switzerland;1. First School of Clinical Medicine, Wenzhou Medical University, Wenzhou, Zhejiang 325000, PR China;2. Institute of Mental Health, Suzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University, Soochow University, Suzhou, Jiangsu 215137, PR China;3. Mengcheng Brain Health Hospital, Mengcheng, Anhui 286000, PR China;4. Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
Abstract:
Forty-six patients with bipolar illness were evaluated with scalp-recorded electroencephalograms. Familial pattern of psychopathology was evaluated between groups with clinically normal and abnormal EEG tracings. Those with abnormal EEGs were noted to have a significantly negative family history of affective disorder when compared to the EEG normal group. These results may support the concept of some patients with mania having an acquired illness which occurs independent from its genetic loading.
Keywords:
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