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| 血清C-反应蛋白与冠心病相关性的研究 | |
| 引用本文： | 宋洁,王海英,曹燕,刘云昆,王正惠,杨新. 血清C-反应蛋白与冠心病相关性的研究[J]. 西南国防医药, 2008, 18(2): 190-191 |
| 作者姓名： | 宋洁 王海英 曹燕 刘云昆 王正惠 杨新 |
| 作者单位： | 1. 成都军区昆明疗养院,云南,昆明,650307 2. 第三军医大学西南医院,重庆,400038 |
| 摘 要： | 目的：探讨超敏血清C-反应蛋白（high—sensitivity c—reactive protein，hs—CRP）与冠心病（coronary heartdisease，CHD）的相关性。方法：随机选取138洌经冠状动脉造影证实的冠心病患者，其中74例稳定型心绞痛（sA）、41例不稳定型心绞痛（UA）、23例急性心肌梗死（AMI）．25例健康者作为对照。用乳胶增强免疫透射比浊法（终点法）检测血清其hs—CRP含量。同时探讨hs—CRP与肌钙蛋白Ⅰ（cTnⅠ）、肌酸激酶（CK）、肌酸激酶同工酶（CKMB）的关系。并参考比较不同hs—CRP水平各组患病数。结果：冠心病各亚组hs—CRP水平均高于对照组（P〈0．05）；UA组血清hs—CRP浓度显著高于SA组；AMI组血清hs—CRP浓度分别显著高于UA组与SA组，均有统计性差异（P＜0．05）。结论：冠心病患者血清hs—CRP水平升高，是冠心病的一项独立危险因子，与冠状动脉粥样硬化斑块内的炎症反应有关；血清hs—CRP水平对冠心病的病变程度具有预测价值。 |
| 关 键 词： | 冠心病 超敏C-反应蛋白 |
| 文章编号： | 1004-0188(2008)02-0190-02 |
| 修稿时间： | 2007-11-15 |
Relationship between high-sensitivity of CRP and coronary heart diseases |
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| SONG Jie,WANG Hai-ying,CAO Yan,LIU Yun-kun,WANG Zheng-hui,YANG Xin. Relationship between high-sensitivity of CRP and coronary heart diseases[J]. Medical Journal of National Defending forces in Southwest China, 2008, 18(2): 190-191 | |
| Authors: | SONG Jie WANG Hai-ying CAO Yan LIU Yun-kun WANG Zheng-hui YANG Xin |
| Affiliation: | SONG Jie1,WANG Hai-ying1,CAO Yan1,LIU Yun-kun1,WANG Zheng-hui1,YANG Xin2 1.Kunming Sanatorium of Chengdu Military Comm,,Kuming,650307,China,2. Southwest Hospital,Third Military Medical University,Chongqing,400038,China. |
| Abstract: | Objective:To investigate the clinical value of high-sensitivity C-reactive protein(hs-CRP) in the diagnosis of coronary heart diseases(CHD).Methods:138 cases of CHD (including 74 cases of stable angina(SA), 41 ones of unstable angina pectoris(UA) and 23 ones of acute myocardial infarction(AMI) and 25 healthy subjects were enrolled in this study. The contents of their serum hs-CRP, troponin I(cTnI), creatine kinase(CK) and MB isoenzyme of creatine kinase(CKMB) were examined. The relationship between hs-CRP a... |
| Keywords: | coronary heart disease high-sensitivity C-reactive protein prediction |
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