| Abstract: | By electrophoresis followed by colorimetric study of the stained gels an increased content of growth hormone and prolactin was found in the pituitary of rats during the development of alloxan diabetes. The STH and prolactin levels 4–5 days after injection of alloxan were higher by 45–58 and 38–43% respectively than in intact animals. Experiments on primary cell cultures using 14C]-L-leucine as labeled precursor revealed increased secretory activity of the somatotrophs and lactotrophs of rats with alloxan diabetes.Laboratory of Biological Standardization of Hormones, Institute of Experimental Endocrinology and Hormone Chemistry, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR N. A. Yudaev.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 88, No. 11, pp. 536–538, November, 1979. |
