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| 228例慢性重型乙型病毒性肝炎预后因素分析 | |
| 引用本文： | 邹圣强,张园海,於学军,史正全,申悦平. 228例慢性重型乙型病毒性肝炎预后因素分析[J]. 齐齐哈尔医学院学报, 2008, 29(9): 1034-1035 |
| 作者姓名： | 邹圣强 张园海 於学军 史正全 申悦平 |
| 作者单位： | 江苏省镇江市第三人民医院肝病研究室,212001;江苏省镇江市第三人民医院肝病研究室,212001;江苏省镇江市第三人民医院肝病研究室,212001;江苏省镇江市第三人民医院肝病研究室,212001;江苏省镇江市第三人民医院肝病研究室,212001 |
| 基金项目： | 镇江市科技计划社会发展项目 |
| 摘 要： | 目的探讨影响慢性重型乙型病毒性肝炎预后的因素。方法对228例慢性重型乙型病毒性肝炎临床资料进行回顾性分析，总的病死率60．1％。结果病死组年龄、肝炎后肝硬化、血清胆红素水平、HBVDNA阳性率、肝性脑病、电解质紊乱、肝肾综合征、上消化道出血、继发感染发生率明显高于好转或治愈组（P〈0．05）；凝血酶原时间（42．02±16．86）秒明显较好转组延长（26．95±6．83）秒，P〈0．01。结论中青年、胆红素血症越高、凝血酶原时间越长、并发肝炎后肝硬化、肝性脑病、电解质紊乱、继发感染、肝肾综合征及消化道出血是影响慢性重型乙型肝炎预后的危险因素。 |
| 关 键 词： | 乙型病毒性肝炎 重型 慢性 预后 流行病学 |
| 修稿时间： | 2008-02-27 |
Analysis of the factors influencing the prognosis of chronic severe hepatitis B |
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| ZOU Sheng-qiang,et al.. Analysis of the factors influencing the prognosis of chronic severe hepatitis B[J]. Journal of Qiqihar Medical College, 2008, 29(9): 1034-1035 | |
| Authors: | ZOU Sheng-qiang et al. |
| Affiliation: | ZOU Sheng - qiang, et al. (Zhengjiang Third Hospital, Zhengjiang, Jiangsu 212000 China) |
| Abstract: | Objective To explore the prognosis factors on the patients with chronic severe hepatitis B.Methods By analyzing the clinical data of 228 cases with chronic severe hepatitis B retrospectively.Fatality rate was 60.1% in patients with chronic severe hepatitis B.Results In death group,old,serum bilirub in level,appearance of HBVDNA positive,hepaticenc ephalopathy,gastrointestinal hemor-rhage,hepatorenal syndrome and secondary infection were higher than that in improvement group(P<0.01).Prothrombin time(PT) in death group was significant higher than that in improvement group.Conclusions Age younger than50-year,high serum bili-rubin,long PT,complicated with hepaticenc ephalopathy,gastrointesinal hemorrhage,hepatorenal syndrome and infection are important factors influencing the prognosis of chronic severe hepatitis B. |
| Keywords: | Viral hepatitis B Severe type Chronic Prognosis Epidemiologic |
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