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糖微康对糖尿病大鼠肾功能保护作用的实验研究
引用本文:林兰,倪青,刘喜明,张润云,薛柳华,王兆礼,楚晓燕.糖微康对糖尿病大鼠肾功能保护作用的实验研究[J].中国实验方剂学杂志,2000,6(1):22-24.
作者姓名:林兰  倪青  刘喜明  张润云  薛柳华  王兆礼  楚晓燕
作者单位:中国中医研究院广安门医院,北京,100053
基金项目:国家"九五"攻关课题(96-906-07)
摘    要:观察糖微康胶囊对糖尿病模型大鼠肾脏病变的影响。结果表明:糖微康可减轻肾小球的高灌注,高滤过,减轻非酶糖基化,调节脂代谢,抗脂质过氧化损伤,从而抑制肾小球系膜细胞增生和系膜基质分泌,延缓肾小球纤维化,硬化进程,保护肾功能。

关 键 词:糖微康胶囊  糖尿病  肾脏病变  中药  药理
文章编号:1005-9903(2000)01-0022-03
收稿时间:1999/7/13 0:00:00
修稿时间:1999年7月13日

Experimental Study on Protection of Renal Function by Tangweikang Capsule in Diabetic Rats
LIN Lan,NI Qing,LIU Xi-ming,ZHANG Run-yun,- XUE Liu-hu,WANG Zhao-li,CU Xiao-yan.Experimental Study on Protection of Renal Function by Tangweikang Capsule in Diabetic Rats[J].China Journal of Experimental Traditional Medical Formulae,2000,6(1):22-24.
Authors:LIN Lan  NI Qing  LIU Xi-ming  ZHANG Run-yun  - XUE Liu-hu  WANG Zhao-li  CU Xiao-yan
Institution:Guanganmen Hospital,China Academy of TCM,Beijing 100053
Abstract:The effect of Tangweikang capsule on nephroses was observed in diabetic rats.The result indicated that Tangweikang capsule could improve nephroses of high infusion and high filtration in glomerulus,inhibit non enzyme glycosylation,regulate lipid metabolism and protect against peroxide damage.It can inhibit mesangial cell proliferation and mesenteric matrix secretion,delay the fibrosis of glomerulus and preserve renal function.
Keywords:Tangweikang capsule  diabetic rats  nephroses
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