| 酸碱对药麻黄与甘草在麻杏甘石汤中的配伍化学研究 |
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| 引用本文： | 裴妙荣,裴香萍,段秀俊. 酸碱对药麻黄与甘草在麻杏甘石汤中的配伍化学研究[J]. 中国中药杂志, 2009, 34(19): 16-18 |
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| 作者姓名： | 裴妙荣 裴香萍 段秀俊 |
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| 作者单位： | 山西中医学院 中药系， 山西 太原 030024 |
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| 基金项目： | 国家自然科学基金面上项目(30472125) |
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| 摘 要： | 目的：考察麻黄与甘草酸碱对药在麻杏甘石汤中配伍前后麻黄碱与甘草酸提取量的变化规律。方法：采用高效液相色谱法对麻黄、甘草单味药提取液、麻黄甘草对药提取液及全方提取液中麻黄碱和甘草酸提取量进行测定。结果：各样品液中麻黄碱变化不明显，全方中甘草酸含量较单味药降低。结论：酸碱对药麻黄、甘草在配伍后麻黄碱与甘草酸基本不形成大分子复合物。
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| 关 键 词： | 麻黄；甘草；酸碱对药；麻杏甘石汤；配伍化学 |
| 收稿时间： | 2009-03-12 |
Compatability chemistry of acid-alkaline pair Medicine of mahuang and gancao in Maxing Ganshi decoction |
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| PEI Miaorong,PEI Xiangping and DUAN Xiujun. Compatability chemistry of acid-alkaline pair Medicine of mahuang and gancao in Maxing Ganshi decoction[J]. China Journal of Chinese Materia Medica, 2009, 34(19): 16-18 |
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| Authors: | PEI Miaorong PEI Xiangping DUAN Xiujun |
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| Abstract: | Objection: To determine the change pattern of ephedrine and glyrihhzine acid in mahuang and gancao pair medicines and Maxingganshi decoction. Method: The contents of ephedrine and glycyrrhizic acid were determined by HPLC in samples of mahuang extracts, gancao extracts, mahuang and gancao pair medicines extracts, and extracts of whole recipe. Result: There were no significant difference in ephedrine contents amoung different samples; the contents of glycyrrhizic acid were lower in decoctions of whole recipe than in gancao decoction. Conclusion: No macromolecular complex was formed by ephedrine and glycyrrhizic acid in decoctions containing mahuang and gancao combination. |
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| Keywords: | mahuang gancao Acid-alkaline Pair Medicine Maxingganshi decoction, compatability chemistry |
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