| 慢性阻塞性肺疾病和肺心病患者血浆TXB2、6-Keto-PGF1a的测定 |
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| 引用本文： | 刘韵蝉,唐筑灵,何燕. 慢性阻塞性肺疾病和肺心病患者血浆TXB2、6-Keto-PGF1a的测定[J]. 贵阳医学院学报, 2002, 27(4): 314-315 |
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| 作者姓名： | 刘韵蝉 唐筑灵 何燕 |
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| 作者单位： | 贵阳医学院附院内科,贵州,贵阳,550004 |
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| 摘 要： | 目的探讨慢性阻塞性肺疾病(COPD)和肺心病患者血浆血栓素(TXB2)和6-酮-前列环素F1a(6-Keto-PGF1a)的变化及临床意义.方法采用放射免疫法测定血浆TXB2、6-Keto-PGF1a的浓度.结果COPD患者血浆TXB2与对照组比较无明显差异(P＞0.05).肺心病急性发作期TXB2明显高于对照组及COPD组,差异有显著性(P＜0.01).COPD组及肺心病组6-Keto-PGF1a与对照组比较差异有显著性(P＜0.01).结论TXB2在肺心病肺动脉高压的发生发展中起着重要的作用.
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| 关 键 词： | 阻塞性肺疾病 肺心病 血栓烷B2 合成前列腺素类 血浆 |
| 文章编号： | 1000-2707(2002)04-0314-02 |
| 修稿时间： | 2002-05-17 |
Measurements of Plasma TXB2,6-Keto-PGF1a in Chronic Obstructive Pulmonary Disease(COPD)and Pulmonary Heart Diseases |
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| LIU Yun chan,TANG Zhu ling,HE Yan. Measurements of Plasma TXB2,6-Keto-PGF1a in Chronic Obstructive Pulmonary Disease(COPD)and Pulmonary Heart Diseases[J]. Journal of Guiyang Medical College, 2002, 27(4): 314-315 |
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| Authors: | LIU Yun chan TANG Zhu ling HE Yan |
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| Abstract: | Objective: To investigate the changes of TXB 2 and 6-Keto-PGF 1a in patients of COPD and pulmonary heart disease.Methods:The radioimmunoassay (RIA) were used to measure levels of plasma TXB 2 and 6-Keto-PGF 1a.Results:Level of plasma TXB 2 in COPD was similar to that of control's (P>0 05).The plasma TXB 2 in pulmonary heart disease patients were higer than those of control's and COPD(P<0 01).the plasma 6-Keto-PGF 1a in COPD and pulmonary heart disease groups were higher than that of control's (P<0 01).Conclusion:The results of this study suggest that TXB 2 have an important effect in the development of high pulmonary arterial Pressure in pulmonary heart disease. |
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| Keywords: | lung disease obstructive heart disease thromboxane B 2 prostaglandins synthetic plasma |
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