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Protective effect of Antrodia Camphorata on bladder ischemia/reperfusion injury |
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| Authors: | Yung-Shun Juan Anita Mannikarottu Shu Mien Chuang Suning Li Alpha D. Lin Lan Chang-Chou Catherine Schuler Robert E. Leggett Robert M. Levin |
| Affiliation: | (1) Department of Urology, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung, Taiwan;(2) Graduate Institute of Medicine, Department of Urology, Kaohsiung Medical University, Kaohsiung, Taiwan;(3) Albany College of Pharmacy, 106 New Scotland Avenue, Albany, NY 12208, USA;(4) Albany Medical College, Albany, NY, USA;(5) Stratton Veterans Affairs Medical Center, Albany, NY, USA;(6) First Affiliated Hospital of Zhengzhou University, Henan, China;(7) Taichung Poh-Ai Hospital, Taichung, Taiwan;(8) Wellshine Biotech Company, Taipei, Taiwan; |
| Abstract: | IntroductionObstructive bladder dysfunction is directly related to ischemia/reperfusion injury characterized by damage to nerves, synapses and smooth muscle cells within the bladder wall. Antrodia Camphorata (AC) has significant antioxidant, antiinflammatory and cell-cycle inhibition properties. The specific aim of this study was to evaluate whether orally administered AC can protect rabbit bladders from the progressive dysfunctions induced by bilateral ischemia/reperfusion (I/R). |
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