| Abstract: | ![]()
The aim of this study was evaluation of enterovirus diagnosis based on isolation of the virus in cell culture from subjects with aseptic neuroinfection conducted in six Provincial Sanitary-Epidemiological Stations in 1995-2000 years. Available data from six Sanitary-Epidemiological Stations indicated that 1429 isolation of enteroviruses from fecal samples of those patients were performed. The most frequently isolated enterovirus serotype was echovirus type 30: 138/203 isolated enteroviruses, but also others enterovirus serotypes were isolated in a study period. In the years 1995 and 1996 the percentage of positive results of isolation was highest with the numbers of 31% and 28.27% respectively. The decrease in positive isolation results has been observed from 1997 year. Negative results of isolation come up to 90% of investigated cases. Only 1.5% of enterovirus isolation attempts finished successfully in 2002 year. The situation when percentage of positive results of isolation is on so low level, the natural alterations in a profile of enterovirus serotype infected population cannot be observed, and serological investigations can be conducted for enterovirus serotypes others than really circulating and causing infections in population. |
