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| 细胞焦亡在心血管疾病中作用的研究进展 | |
| 引用本文： | 翁秀朱,贾海波. 细胞焦亡在心血管疾病中作用的研究进展[J]. 中国动脉硬化杂志, 2021, 29(9): 807-813 |
| 作者姓名： | 翁秀朱 贾海波 |
| 作者单位： | 哈尔滨医科大学附属第二医院心血管内科 心肌缺血教育部重点实验室,黑龙江省哈尔滨市 150001 |
| 基金项目： | 国家自然科学基金面上项目(81671763) |
| 摘 要： | 心血管疾病(CVD)已成为全球范围内的主要死亡原因之一.尽管目前对CVD的研究已取得一定进展,但仍有诸多问题有待进一步研究.近年新发现的细胞焦亡是一种伴随着炎症反应的细胞程序性死亡,研究显示其在CVD的发生发展中发挥重要作用.本文对细胞焦亡在动脉粥样硬化、心肌梗死、糖尿病性心肌病、心肌炎等CVD中的作用及机制进行了综述... |
| 关 键 词： | 细胞焦亡 心血管疾病 炎症小体 |
| 收稿时间： | 2020-07-26 |
| 修稿时间： | 2020-09-24 |
Research progress of the role of pyroptosis in cardiovascular disease |
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| WENG Xiuzhu,JIA Haibo. Research progress of the role of pyroptosis in cardiovascular disease[J]. Chinese Journal of Arteriosclerosis, 2021, 29(9): 807-813 | |
| Authors: | WENG Xiuzhu JIA Haibo |
| Affiliation: | Department of Cardiology, the Second Affiliated Hospital of Harbin Medical University & Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin, Heilongjiang 150001, China |
| Abstract: | Cardiovascular disease (CVD) has become one of the leading causes of death worldwide. Although the research on CVD has made some progress, there are still many problems to be further studied. In recent years, the newly discovered pyroptosis is a kind of programmed cell death accompanied by inflammatory reaction. Studies have shown that pyroptosis plays an important role in the occurrence and development of CVD. This article reviews the role and mechanism of pyroptosis in atherosclerosis, myocardial infarction, diabetic cardiomyopathy, myocarditis and other CVD. |
| Keywords: | pyroptosis cardiovascular disease inflammasome |
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