| 急性白血病免疫分型的临床应用 |
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| 引用本文： | 宋光,于增国,栾桂红. 急性白血病免疫分型的临床应用[J]. 大理医学院学报, 2002, 11(2): 45-47 |
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| 作者姓名： | 宋光 于增国 栾桂红 |
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| 作者单位： | 大连大学医学院,辽宁大连,116622;大连市中心医院,辽宁大连,116622 |
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| 摘 要： | 目的：研究急性白血病(AL)细胞抗原表达特点及临床意义。方法：采用流式细胞仪(FCM)对72例初诊急性白血病患进行免疫分型。结果：AML患均表达两种以上髓系抗原,其中部分伴有淋系抗原(CD7)表达,M7表达巨核细胞抗原。ALL患均表达淋系抗原,部分表达一种或两种髓系抗原。1例混合型白血病同时表达两种以上淋系和髓系抗原标志。4例慢粒急淋变既表达髓系抗原又表达淋系抗原。结论：免疫分型是细胞形态学和细胞化学染色基础上对于急性白血病诊断与分型的重要补充。
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| 关 键 词： | 急性白血病 免疫分型 流式细胞仪 |
| 文章编号： | 1004-4442(2002)02-0045-03 |
| 修稿时间： | 2002-01-09 |
The Clinical Application Of Immunophenotyping In Acute Leukemia |
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| SING Guang,YU Zeng-guoLuan Gui-hong. The Clinical Application Of Immunophenotyping In Acute Leukemia[J]. Journal of Dali Medical College, 2002, 11(2): 45-47 |
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| Authors: | SING Guang YU Zeng-guoLuan Gui-hong |
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| Affiliation: | Medical Collegl of Dalian University 116622 China |
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| Abstract: | Obiectuve:To investigate the expression speciality and clinical signification of acute leukemia(AL)cells antigens.Methods:To collect 72 cases who were primary acute leukemia patient to make immunologic analysis by flow cytometry(FCM) Results:ALL patients all express lymphoid antigens,and some express one or two myeloid antigens.AML patients all express myeloid markers.and some of them express lymphoid antigen CD7.M7 express megakaryocytic markers.One case is hybrid acute leukemia that express more than markers of both lymphoid and myeloid origins.Four cases who inversed from CML to ALL express myeloid and lymphoid antigens.Conclusion:Immunonpyentyping is an important sapplement to the diagnosis and typing of the acute leykemia on the base of the morphology and cytochemistiy. |
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| Keywords: | acuteleukemia immunopgenotyping flowcytommetry |
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