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益生菌的临床研究进展
引用本文:赵紫楠,陈丽,金鹏飞,李可欣,田超,胡欣.益生菌的临床研究进展[J].中国药业,2021(8):96-96,I0001-I0006.
作者姓名:赵紫楠  陈丽  金鹏飞  李可欣  田超  胡欣
作者单位:北京医院药学部·药物临床风险与个体化应用评价北京市重点实验室·国家老年医学中心·中国医学科学院老年医学研究院;中央军委联合参谋部警卫局卫生保健处;北京医院临床试验研究中心;国家儿童医学中心·首都医科大学附属北京儿童医院药学部
基金项目:国家科技重大专项课题[2017zx09101001]。
摘    要:目的为益生菌的临床应用提供参考。方法系统检索益生菌临床应用的理论基础、研究进展和临床使用现状。结果与结论益生菌在儿科疾病、呼吸系统疾病、消化系统疾病、心血管疾病、精神疾病、肿瘤中的应用均有较好的有效性与安全性。高质量、大型的临床研究有待进一步开展,以规范和推广益生菌在临床的使用。

关 键 词:益生菌  肠道菌群  儿科疾病  消化系统疾病  心血管疾病  精神疾病  进展

Clinical Research Progress of Probiotics
ZHAO Zinan,CHEN Li,JIN Pengfei,LI Kexin,TIAN Chao,HU Xin.Clinical Research Progress of Probiotics[J].China Pharmaceuticals,2021(8):96-96,I0001-I0006.
Authors:ZHAO Zinan  CHEN Li  JIN Pengfei  LI Kexin  TIAN Chao  HU Xin
Institution:(Department of Pharmacy,Assessment of Clinical Drugs Risk and Individual Application Key Laboratory,Beijing Hospital·National Center of Gerontology·Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing,China 100730;Health Service Department of the Guard Bureau of the Joint Staff Department,Beijing,China 100017;Beijing Hospital Clinical Trial Center,Beijing,China 100730;Department of Pharmacy,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing,China 100045)
Abstract:Objective To provide a reference for the clinical application of probiotics.Methods The theoretical basis,research progress and clinical application of probiotics were systematically searched.Results and Conclusion Probiotics are effective and safe in the treatment of pediatric diseases,respiratory diseases,digestive diseases,cardiovascular diseases,mental diseases and tumors.High-quality,large-scale clinical research needs to be further carried out to standardize and promote the clinical use of probiotics.
Keywords:probiotics  intestinal flora  pediatric diseases  digestive system diseases  cardiovascular diseases  mental diseases  progress
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