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Diagnostic reliability of magnetic resonance imaging for central nervous system syndromes in systemic lupus erythematosus: a prospective cohort study |
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| Authors: | Yasuhiro Katsumata Masayoshi Harigai Yasushi Kawaguchi Chikako Fukasawa Makoto Soejima Tokiko Kanno Katsuji Nishimura Takayuki Yamada Hisashi Yamanaka Masako Hara |
| Affiliation: | (1) Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku Tokyo, 162-0054, Japan;(2) Department of Pharmacovigilance, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku Tokyo, 113-8519, Japan;(3) Department of Psychiatry, Tokyo Women's Medical University School of Medicine, 8-1 Kawada-cho, Shinjuku-ku Tokyo, 162-8666, Japan;(4) Department of Radiology, Tokyo Women's Medical University School of Medicine, 8-1 Kawada-cho, Shinjuku-ku Tokyo, 162-8666, Japan |
| Abstract: | BackgroundPrevious studies of magnetic resonance imaging (MRI) as a diagnostic tool for central nervous system (CNS) syndromes in systemic lupus erythematosus (SLE) contained several limitations such as study design, number of enrolled patients, and definition of CNS syndromes. We overcame these problems and statistically evaluated the diagnostic values of abnormal MRI signals and their chronological changes in CNS syndromes of SLE. |
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