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A double-blind, randomized, comparative trial of itraconazole versus terbinafine for 2 weeks in tinea capitis
Authors:Jahangir,Hussain,UL Hasan,&   Haroon
Affiliation:Department of Dermatology, King Edward Medical College/Mayo Hospital, Lahore, Pakistan
Abstract:
In this randomized, double-blind study, the efficacy and safety of oral itraconazole ( n  = 28) and terbinafine ( n  = 27), each given for 2 weeks, was compared in patients with tinea capitis. Trichophyton violaceum was the major pathogen in both groups (82.1% and 88.9%, respectively). The final evaluation at week 12 showed a cure rate of 85.7% and 77.8%, respectively ( P  > 0.05). Adverse events noted were mild and did not warrant discontinuation of therapy.
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