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| 多层螺旋CT评价口腔鳞癌p53蛋白表达 | |
| 引用本文： | 吕玉波,李传亭,王涛,刘学静,吕京光,柳澄,武乐斌. 多层螺旋CT评价口腔鳞癌p53蛋白表达[J]. 医学影像学杂志, 2004, 14(1): 25-28 |
| 作者姓名： | 吕玉波 李传亭 王涛 刘学静 吕京光 柳澄 武乐斌 |
| 作者单位： | 山东省医学影像学研究所,山东,济南,250021 |
| 摘 要： | 目的：评价口腔鳞癌MSCT征象与p53蛋白表达的关系。方法：39例口腔鳞癌术前行多层螺旋CT扫描。采用免疫组化方法，对病理标本行p53蛋白测定，统计学分析p53蛋白与MSCT征象的相关性。结果：口腔鳞癌的MSCT征象如肿瘤边界、大小、增强情况及有无淋巴结转移与p53蛋白明显相关，而肿瘤密度与p53蛋白则无明显关系。结论：MSCT征象与口腔鳞掰p53蛋白表达有明显相关性，有助于对其预后进行评价。 |
| 关 键 词： | 口腔鳞癌 p53蛋白 体层摄影术 X线计算机 免疫组织化学 |
| 文章编号： | 1006-9011(2004)01-0025-04 |
| 修稿时间： | 2003-11-13 |
MSCT evaluating p53 expression in oral squamous cell carcinomas |
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| LV Yu bo,LI Chuan ting,WANG Tao,et al.. MSCT evaluating p53 expression in oral squamous cell carcinomas[J]. Journal of Medical Imaging, 2004, 14(1): 25-28 | |
| Authors: | LV Yu bo LI Chuan ting WANG Tao et al. |
| Affiliation: | LV Yu bo,LI Chuan ting,WANG Tao,et al.Shandong Medical Imaging Institute,Jinan 250021,China |
| Abstract: | Objective:To evaluate the relationship between Mutislice CT(MSCT) and the expression of p53 in cases of oral squamous cell carcinomas.Methods:MSCT features of 39 cases of oral squamous cell carcinomas were analyzed. p53 was measured with immunohistochemical method in all histologic specimens. The results were compared with CT features.Results:Oral squamous cell carcinomas MSCT features like verge, size, extent of contrast enhancement,enhanced phase and lamph node metastasis correlated well with p53 ,but the density did not correlated with it.Conclusion:MSCT could evaluate the expression of p53. It is useful in estimating the prognosis of oral squamous cell carcinomas. |
| Keywords: | Oral squamous cell carcinoma p53 protein Tomography X ray computed Immunocytochemistry |
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