三子咳喘胶囊治疗慢性支气管炎痰湿阻肺证疗效观察

目的：验证三子咳喘胶囊对慢性支气管炎（痰湿阻肺证）的疗效,并对其安全性作出客观评价.方法：采用随机、双盲、平行对照试验,将慢性支气管炎痰湿阻肺证患者58例随机分为试验组43例,对照组15例.试验组口服三子咳喘胶囊2粒/次,空白模拟剂3粒/次,每日3次;对照组口服桂龙咳喘宁胶囊5粒/次,每日3次,疗程均为10天.结果：临床总体疗效：试验组临床控制率23.26%,显效率39.53%,有效率37.21%,愈显率62.79%;对照组临床控制率20.00%,显效率33.33%,有效率46.67%,愈显率53.33%.中医证候疗效：试验组临床控制率20.93%,显效率37.21%%,有效率41.86,愈显率58.14%;对照组临床控制率20.00%,显效率33.33%,有效率46.67%,愈显率53.33%.两组对咳嗽、咳痰、喘息均有明显疗效.以上疗效组间均无明显差异（P＞0.05）.结论：三子咳喘胶囊临床疗效确切,未发现明显毒副反应,与桂龙咳喘宁胶囊相仿.

Curative Effects of Sanzi Kechuan Capsule in Treating Chronic Bronchitis with Syndrome of Phlegm-Dampness Accumulated in the Lung

Objective:To certificate the curative effects of Sanzi Kechuan Capsule in treating chronic bronchitis with syndrome of phlegm-dampness accumulated in the lung,and evaluate objectively its safety.Methods:58 patients of chronic bronchitis with syndrome of phlegm-dampness accumulated in the lung were divided into experimental group(43 cases),and control group(15 cases)according to the methods of random control,double-blind and parallel control experiment.The former were orally given Sanzi Kechuan Capsule 2 capsules per time and Simulative Capsule 3 capsules per time,three times a day.While the latter were given Guilong Kechuan Capsule 5 capsules per time,three times a day,and each group had a treatment course of 10 days.Results:The whole curative effects:The clinical control rate,improving rate,effective rate and recovery and excellence rate of the experimental group were 23.26%,39.53%,37.21% and 62.79%,while those of control group were 20.00%,33.33%,46.67% and 53.33%.The curative effects of TCM syndrome:The clinical control rate,improving rate,effective rate and recovery and excellence rate of experimental group were 20.93%,37.21%,41.86% and 58.14%,while those of control group were 20.00%,33.33%,46.67% and 53.33%.Two groups had apparent curative effects on cough,cough of phlegm and gasp.There were no apparent differences between two groups in the curative effects(P>0.05).Conclusion:Sanzi Kechuan Capsule has exact curative effects.It has no obvious noxious and side effects and is similar to Guilong Kechuan Capsule.