血液病患者感染的病原菌分布及耐药性分析

目的了解血液患者感染病原菌分布情况及耐药性分析。方法用KB纸片扩散法对血液病患者分离的146株病原菌进行药敏试验统计分析。结果391例血液病患者标本,培养出146株,阳性率37.34%,其中G-菌占50%,G 菌占26.71%,真菌占23.29%。大肠埃希菌、铜绿假单胞菌、肺炎克雷伯菌、金黄色葡萄球菌、表皮葡萄球菌、白色念珠菌为常见菌。结论血液病患者感染病原菌以G-菌为主,G-菌以亚胺培南最为敏感,其次是头孢哌酮/舒巴坦;G 以万古霉素、呋喃妥因最为敏感。

Distribution and drug resistance analysis of pathogens causing infection in hematological patients

OBJECTIVE To investigate the distribution and drug resistance of pathogens causing infection in hematological patients.METHODS The antibiotic susceptibility of 146 strains pathogens from hematological patients were analyzed by Kirby-Bauer test with statistics.RESULTS A total of 146 strains of pathogens were isolated from 391 cases of hematological patients,the isolation rate was 37.34%,50% of which were Gram-negative bacteria,and 26.70% were Gram-positive ones,23.28% were fungi.Escherichia coli,Pseudomonas aeruginosa,Candida albicans,Klebsiella pneumoniae,Staphylococcus aureus and S.epidermidis often appeared.CONCLUSIONS The main pathogens causing infection in patients were Gram-negative bacteria,Gram-negative bacteria were especially sensitive to imipenem,the next was cefoperazone/sulbactam.Gram-positive bacteria were especially sensitive to vancomycin and nitrofurantoin.