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Diagnosis of children withidiopathic inflammatorymuscle disease.

??Idiopathic inflammatory sympathies are a group of rare autoimmune disorders??characterized by inflammation in striated muscle. Dermatomyositis is the most common subtype in children.Though a number of diagnostic criteria have been proposed??the diagnosis of dermatomyositis is based on a combination of clinical??laboratory and electromyography findings.Typical features are subacute-onset?? proximal??symmetric muscle weakness??pathognomonic skin rashes.Muscle biopsy demonstrated inflammatory infiltrates confined to perimysium??often around blood vessels??and perifascicular muscle fiber atrophy. The uses of magnetic resonance imaging of skeletal muscles??detection of myositis-specific autoantibodies and nailfold capillaroscopy have become useful additions to our diagnostic test.