| 丹皮多糖一般药理学研究 |
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| 引用本文： | 彭代银,韩岚,张丛芬,沈业寿,赵帜平.丹皮多糖一般药理学研究[J].安徽中医学院学报,2005,24(2):30-32. |
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| 作者姓名： | 彭代银 韩岚 张丛芬 沈业寿 赵帜平 |
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| 作者单位： | 安徽中医学院药学院,安徽,合肥,230031;安徽大学生命科学院 |
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| 基金项目： | 安徽省科技攻关项目;Z0640023; |
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| 摘 要： | 目的: 观察丹皮多糖(PSM)主要药效学以外的药理作用, 为临床用药提供参考。方法:观察用药前后大鼠、小鼠自主活动行为能力,家猫呼吸频率、呼吸深度和狗血压、心率的变化情况。结果: 用药后大鼠、小鼠自主活动行为能力,家猫呼吸频率、呼吸深度及狗血压、心率均无明显变化。用药前后比较, 差异无显著性(P>0. 05)。结论: 在药效剂量下PSM对大鼠、小鼠的神经系统,家猫呼吸系统及狗的心血管系统系统均无明显影响。
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| 关 键 词： | 丹皮多糖 一般药理学 |
| 文章编号： | 1000-2219(2005)02-0030-03 |
| 修稿时间： | 2005年3月2日 |
Study on the General Pharmacological Action of Polysaccharides from Mudan Cortex |
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| PENG Dai-yin,HAN Lan,ZHANG Cong-fen,SHEN Ye-shou,CHAO Zhi-ping.Study on the General Pharmacological Action of Polysaccharides from Mudan Cortex[J].Journal of Anhui Traditional Chinese Medical College,2005,24(2):30-32. |
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| Authors: | PENG Dai-yin HAN Lan ZHANG Cong-fen SHEN Ye-shou CHAO Zhi-ping |
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| Abstract: | Objective: To observe the general pharmacological action of polysaccharides from mudan cortex(PSM) except main pharmacodynamics. Method: The blood pressure , heart beat rate , heart rhythm in dogs , respiratory rate and depth of respiration in cats and the times of freedom movement in mice and rats were studied before and after given PSM. Result: The blood pressure , heart beat rate , heart rhythm , respiratory rate and depth of respiration freedom movement in animals have no obvious difference after given PSM(P>0.05).Conclusion: PSM in effective dose have no obvious influence on nervous system in mice and rats, respiratory system(respiration rhythms, respiration depth)in cats and cardiovascular system in dogs. |
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| Keywords: | Polysaccharides from mudan cortex General pharmacology |
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