| 核转录因子NF-κB研究 |
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| 引用本文： | 郭金昊,姜月华,杨传华,陈永志,孙楠楠. 核转录因子NF-κB研究[J]. 长春中医药大学学报, 2016, 32(2): 380-382. DOI: 10.13463/j.cnki.cczyy.2016.02.059 |
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| 作者姓名： | 郭金昊 姜月华 杨传华 陈永志 孙楠楠 |
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| 作者单位： | 山东中医药大学,济南,250011;山东中医药大学附属医院,济南,250011 |
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| 基金项目： | 山东省科技发展计划项目(No.2014GSF119011);泰山学者岗位建设资金资助(2012-55)。 |
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| 摘 要： | 研究表明,作为能够影响细胞生存、变异和增殖的重要核转录因子,NF-κB在近30年的探索中取得了丰硕成果。尤其是在癌症、骨骼系统及呼吸系统的发病机制研究中取得很大进展。NF-κB作为转录因子在各种生理过程中获得多重生物学意义。中药单方、复方等皆可调控NF-κB通路相关基因和蛋白,药效良好,为今后治疗提供了新的思路。
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| 关 键 词： | 核转录因子 NF-κB 癌症 骨骼 呼吸 |
Nuclear transcription factor nf-kappa B of the latest research progress |
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| GUO Jinhao,JIANG Tuehua,TANG Chuanhua,CHEN Tongzhi,SUN Nannan. Nuclear transcription factor nf-kappa B of the latest research progress[J]. Journal of Changchun College of Traditional Chinese Medicine, 2016, 32(2): 380-382. DOI: 10.13463/j.cnki.cczyy.2016.02.059 |
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| Authors: | GUO Jinhao JIANG Tuehua TANG Chuanhua CHEN Tongzhi SUN Nannan |
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| Abstract: | As an important nuclear transcription factor that can affect the survival,variation and proliferation of cells,NF-kappa B has achieved fruitful results in recent thirty years. Great progress has been made in the research of the pathogenesis of cancer,skeletal system and respiratory system. Chinese medicine has been reported that both uni-lateral and compound can regulate the NF-κB pathway related genes and proteins,the effect is good,to provide new i-deas for the future treatment. |
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| Keywords: | nuclear transcription factor NF-κB cancer skeleton respiratory |
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