| MicroRNA 与胰腺癌关系的研究进展 |
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| 引用本文： | 于琦 综述 赵平|马洁|王成锋 审校. MicroRNA 与胰腺癌关系的研究进展[J]. 中国普通外科杂志, 2013, 22(3): 344-349 |
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| 作者姓名： | 于琦 综述 赵平|马洁|王成锋 审校 |
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| 作者单位： | 于琦 (北京协和医学院中国医学科学院肿瘤医院腹部外科,北京,100021)； |
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| 摘 要： | 胰腺癌是恶性程度最高、预后最差的恶性肿瘤之一，其相关的分子机制的研究具有重要的临床意义。微小RNA（microRNA，miRNA）通过调节基因的表达参与多种生物医学过程，其异常表达与肿瘤的发生发展及预后密切相关。笔者就miRNA与胰腺癌的诊断、治疗和预后关系的研究进展做一综述。
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| 关 键 词： | 胰腺肿瘤；微RNAs；综述文献 |
| 收稿时间： | 2012-12-06 |
| 修稿时间： | 2013-02-28 |
MicroRNA in pancreatic cancer: recent progress |
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| YU Qi,ZHAO Ping,MA Jie,WANG Chengfeng. MicroRNA in pancreatic cancer: recent progress[J]. Chinese Journal of General Surgery, 2013, 22(3): 344-349 |
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| Authors: | YU Qi ZHAO Ping MA Jie WANG Chengfeng |
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| Affiliation: | (Department og Abdominal Surgery, Cancer Hospital of Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021) |
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| Abstract: | Pancreatic cancer is one of the most malignant diseases with the poorest prognosis, so the investigation into its pathogenesis is of great clinical importance. MicroRNAs (miRNAs) participate in various biological processes via controlling gene expression, and the aberrant expression of miRNAs is closely associated with initiation and progression of tumors as well as correlated with the prognosis. In this paper, the authors present the recent advances regarding the relations of miRNAs with the diagnosis, treatment and prognosis of pancreatic cancer. |
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| Keywords: | Pancreatic Neoplasms MicroRNAs Review |
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