非甾体抗炎药物临床应用分析

目的 通过评估非甾体抗炎药物在我院的使用情况,监测此类药物用药的合理性及药物利用情况.方法 分析2010年1-12月我院门诊处方.结果 共调查2010年度门诊处方304 089张,其中含NSMDs的处方30 503张,占总处方的10.03％.使用频率前10位的药物包括尼美舒利胶囊(12 278张)、25 mg阿司匹林(5098张)、美洛昔康分散片(3193张)、尼美舒利颗粒(2143张)、丙氧氨酚片(2139张)、萘丁美酮胶囊(2129张)、布洛芬片(968张)、尼美舒利分散片(906张)、洛索洛芬颗粒(676张)、布洛芬混悬液(506张).应用此类药物最多的是骨科(7354张,21.77％),其后依次为急诊科(6968张,20.62％)、神经内科(3879张,11.48％)、康复科(3536张,10.46％)、风湿科(2298张,6.80％)等.用药总量前10种NSAIDs的药物利用指数均＜1.结论 我院门诊非甾体抗炎药物的利用基本合理.

Analysis of clinical application of nonsteroidal anti-inflammatory drugs

Objective To monitor the rational use of nonsteroidal anti-inflammatory drugs (NSAIDs).Methods Analysis on outpatient prescription in our hospital from January to December in 2010 was performed.Results Totally 304089 outpatient prescriptions were evaluated,including 30503 prescriptions of NSAIDs.Top 10prescribed medicines were:Nimesulide capsule (12278 prescriptions),25mg aspirin (5098 prescriptions),Meloxicam dispersible tablet (3193 prescriptions),Nimesulide granules (2134 prescriptions),Propoxyphene Napsylate and Paracetamol Tablets (2139 prescriptions)Nabumetone capsule (2129 prescriptions),ibuprofen tablet(968 prescriptions),Nimesulide dispersible tablet (906 prescriptions),loxoprofen granules (676 prescriptions)and Ibuprofen Suspension (506 prescriptions).NSAIDs were used most frequently in orthopedics (7354 prescriptions,21.77％ ),followed by emergency department (6968 prescriptions,20.62％ ),neurology (3879 prescriptions,11.48％ ),rehabilitation department ( 3536prescriptions,10.64％ ) and Rheumatology ( 2298 prescriptions,6.80％ ).The drug utilization index value of all these ten drugs was lower than 1.Conclusion The outpatient use of NSAIDs in our hospital is rational.