阿奇霉素治疗呼吸道感染

目的 :观察阿奇霉素对呼吸道感染的疗效。方法 :75例呼吸道感染病人随机分为阿奇霉素组 4 0例 [男性 2 6例 ,女性 14例 ,年龄 34a±s10a (18～6 0a) ],用阿奇霉素 0 .2 5g +5%葡萄糖注射液 50 0mL ,iv ,gtt ,qd ,首日剂量加倍 ,疗程 5d ;头孢唑林组 35例 [男性 2 3例 ,女性 12例 ,年龄 33a± 11a(18～ 59a) ],用头孢唑林 2 g +5%葡萄糖注射液2 50mL ,iv ,gtt ,bid ,疗程 5d。结果 :阿奇霉素组和头孢唑林组的总有效率分别为 95%和 94 % ,细菌清除率分别为 97%和 97% ,不良反应发生率分别为 8%和 9% ,P >0 .0 5。结论 :阿奇霉素是治疗呼吸道感染有效、不良反应少的药物

Azithromycin in treating respiratory infections

AIM: To observe the efficacy of azithromycin in treating respiratory infections. METHODS: Patients ( n =75) with respiratory infections were randomly divided into 2 groups. Patients ( n =40) as treatment group [M26, F14; age (34± s 10)a, 18～60 a] were treated with azithromycin 0.25 g+5 % glucose injection 500 mL, iv, gtt, qd for 5 d, double dose on the first day. The other 35 patients in cefazolin group [M23, F12; age (33±11)a, 18～59 a] were treated with cefazolin 2 g+5 % glucose injectioon 250 mL, iv, gtt, bid for 5 d. RESULTS: The total efficacy rates of azithromycin and cefazolin were 95 % and 94 %, the bacterial clearance rates were 97 % and 97 %, adverse reations occured in 8 % and 9 %, respectively ( P >0.05). CONCLUSION: Azithromycin in treating respiratory infections is safe and effective.