深圳市婴幼儿腹泻中肠道腺病毒感染的流行特点调查

目的：了解深圳市婴幼儿腹泻患儿肠道腺病毒的感染情况。方法:应用聚合酶链反应技术（PCR）对195份婴幼儿腹泻标本进行腺病毒DNA检测，并使用Rsa I内切酶对扩增产物进行限制性内切酶图谱分析,以鉴别肠道腺病毒型别。结果：婴幼儿腹泻标本腺病毒DNA检测的阳性率为13.33％（26／195）。肠道腺病毒40型的感染率为2.56％（5／195），肠道腺病毒41型的感染率为8.21％（16／195），其他型别腺病毒的感染率为2.56％（5／195），发热是腺病毒感染的特征性的临床表现。结论：肠道腺病毒40型和41型是引起深圳市婴幼儿腹泻的重要病原，其中又以肠道腺病毒41型感染为主。

Studies on epidemic feature of enteric adenoviruses infection in feces of infants with diarrhea in Shenzhen

OBJECTIVE: To estimate the enteric adenoviruses infection in feces of infants with diarrhea in Shenzhen. METHODS: All 195 fecal samples of infants were tested by PCR. Amplimers were analysed by Rsa I endonucleases and the type of enteric adenovirus identified. RESULTS: The positive rate of adenovirus DNA in fecal samples was 13.33% (26/195) while the prevalence rates of enteric adenovirus type 40, adenovirus type 41 and the other type of adenovirus were 2.56% (5/195), 8.21% (16/195) and 2.56% (5/195) respectively. Fever was the characteristic symptom of adenovirus infection. CONCLUSION: Enteric adenovirus type 40 and 41 were important pathogens which caused infant diarrhea in Shenzhen, with latter the majorty.