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Actions of somatostatin on lipid metabolism in mouse cerebral cortex slices
Authors:R E Catalán  A M Martínez  M D Aragonés  J E Godoy
Affiliation:1. Departamento de Bioquímica y Biología Molecular, Centro de Biología Molecular (CSIC-UAM), Universidad Autónoma de Madrid, Madrid-34 Spain;2. Departamento de Bioquímica, Colegio Universitario Arcos de Jalón, Madrid-17 Spain
Abstract:
Cerebral cortex slices from mice were used to investigate the variations of lipid metabolism by somatostatin. Somatostatin decreased [14C]acetate incorporation into all lipid fractions significantly. Likewise, the peptide evoked a decrease of triglyceride lipase activity. The incorporation of [32P]orthophosphate into phospholipids was diminished by somatostatin. These results add more information about the effects of somatostatin in cerebral cortex.
Keywords:somatostatin  brain cortex  lipid metabolism
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