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放疗化疗联合治疗局部晚期非小细胞肺癌43例
引用本文:康延志,任惠娟. 放疗化疗联合治疗局部晚期非小细胞肺癌43例[J]. 菏泽医学专科学校学报, 2003, 15(2): 21-22
作者姓名:康延志  任惠娟
作者单位:菏泽市肿瘤防治医院,山东,菏泽,274029;菏泽市肿瘤防治医院,山东,菏泽,274029
摘    要:目的 探讨以顺铂为主的化疗方案加放疗对局部晚期非小细胞肺癌的疗效。方法 86例局部晚期非小细胞肺癌患随机分为治疗组及对照组各43例,放疗方案以CAP、EP、MVP或MOP,每人至少化疗两个周期,化疗后10~14天放射治疗,放疗采用^60Co外照射。结果 治疗组有效率83.7%,中位生存期14.5个月,对照组有效率67.4%,中位生存期10个月,两组不良反应为骨髓抑制、胃肠道反应。结论 以顺铂为主的化疗方案加放疗治疗局部晚期非小细胞肺癌的疗效较高,可提高肿瘤的局部控制率和延长生存期。

关 键 词:非小细胞肺癌/放射疗法  肿瘤  肺癌/药物疗法
文章编号:1008-4118(2003)02-0021-02
修稿时间:2002-11-23

Combination of chemotherapy and radiotherapy used in local advanced non-small cell lung cancer(Nsds)
KANG Yan - zhi,et al. Combination of chemotherapy and radiotherapy used in local advanced non-small cell lung cancer(Nsds)[J]. Journal of Heze Medical College, 2003, 15(2): 21-22
Authors:KANG Yan - zhi  et al
Abstract:Objective To research the effects of combination of chemotherapy and radiotherapy used in local advanced non - small cell lung cancer. Methods 86 patients were divided into two groups. In the treatment group, 43 cases were treated with CAP,EP and MVP or MOP. Eeveryone was used two circle of radiotherapy after chemotherapy 10 - 14days. Results The effective rates of the former and the latter groups were 83. 7% and 67. 4% (P<0.01) The median survival time was 14. 5 months and 10 months. Toxicities were myelosuppression and gastrointestinal tract toxicities. Conclusion The chemotherapy group was better improving the local control and ultimate outcome.
Keywords:non - small cell lung cancer /radiotherapy  tumor  lung cancer/ chemotherapy
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