389例结直肠癌合并癌性贫血相关因素分析

目的:分析389例结直肠癌患者的性别、年龄、肿瘤发生部位、TNM分期、分化程度、术前血清白蛋白水平及大便隐血与癌性贫血的相关性。方法:回顾性分析389例结直肠癌患者临床资料,按2009年AJCC结直肠癌TNM分期法(第7版)进行分期,采用SPSS 17.0软件分析结直肠癌贫血相关因素。结果:389例结直肠癌患者贫血总发生率为44.0%,右半结肠癌(P<0.05)、高TNM分期(P<0.05)、低白蛋白水平(P<0.05)和大便隐血阳性(P<0.05)的患者更易出现贫血,性别、年龄及分化程度与贫血发生无明显相关性。结论:结直肠癌的部位、分期、白蛋白水平及大便隐血是癌性贫血发生的危险因素。

CorrelativeFactors Analysis of Cancer-Related Anemia in 389 Cases of Colorectal Cancer

Objective: To analyze correlative factors of colorectal cancer-related anemia including gender,age,tumor location,clinical stage,degree of tumor differentiation,preoperative serum albumin concentration and fecal occult blood.Methods: Clinical data of 389 colorectal cancer patients were analyzed retrospectively,TNM staging(2009 version) for colorectal cancer of American Joint Committee on Cancer was adopted and statistical analysis of data was used by SPSS 17.0.Results: The incidence of anemia was 44.0%,the patients of right colon cancer(P<0.05),higher TNM stage(P<0.05),lower albumin concentration(P<0.05) and positive fecal occult blood(P<0.05) suffered anemia easily,while gender,age,and degree of tumor differentiation(P>0.05) were not associated with anemia.Conclusion: Tumor location,clinical stage,albumin concentration and fecal occult blood are risk factors of colorectal cancer-related anemia.