1969-2002年瑞典食管静脉曲张住院患者的预后有所改善

食管静脉曲张是肝硬化的并发症，其治疗方案在近30年来有显变化。该研究目的是评价1969—2002年来瑞典的食管静脉曲张患的预后是否有所改善。链接了1969--2002年瑞典医院出院登记处和国立卫生委员会的死因登记处的记录资料，根据国际疾病分类确定的-8、-9和-10患和随访的所有食管静脉曲张患。共有12281例食管静脉曲张住院患，所有患5年存活率的增加仅发生在1969—1979年，而不是1990-2002年。女性较男性，年轻患较老年患，近十年的住院患较前几十年的住院患有较高的存活率。作发现在研究期间因食管静脉曲张引发的死亡率明显降低，但其他原因引起的死亡率并未降低。总之，1969—2002年间，瑞典因食管静脉曲张而入院患的死亡率降低。1年和5年死亡率降低非常显，

Improved prognosis for patients hospitalized with esophageal varices in Sweden 1969- 2002

Liver cirrhosis may be complicated by the development of esophageal varices. The treatment of esophageal varices has changed radically during the last 30 years. Our aim was to study whether the prognosis for patients with esophageal varices had improved in Sweden between 1969 and 2002. We linked register data from the Hospital Discharge Register and from the Causes of Death Register at The National Board of Health in Sweden between 1969 and 2002 to identify and follow-up all patients with esophageal varices according to International Classification of Diseases-8, -9, and -10. There were 12, 281 patients hospitalized with esophageal varices, and for all patients there was an increase in the 5-year survival in the years between 1969 and 1979 as opposed to the years between 1990 and 2002. Better survival occurred for women compared with men, for younger patients compared with older, and for patients hospitalized in the latest decade compared with the earlier decades. We found a significant decrease in the mortality caused by esophageal varices during years studied but no decrease attributable to other causes. In conclusion, mortality for patients hospitalized with esophageal varices in Sweden decreased between 1969 and 2002. The decrease is seen for both 1-and 5-year mortality,