Aliskiren and Valsartan Reduce Myocardial AT1 Receptor Expression and Limit Myocardial Infarct Size in Diabetic Mice |
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| Authors: | Yumei Ye Jinqiao Qian Alexander C. Castillo Jose Regino Perez-Polo Yochai Birnbaum |
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| Affiliation: | (1) The Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, MRB 5:108, 301 University Blvd., Galveston, TX 77555, USA;(2) Department of Anesthesiology, The First Affiliated Hospital of Kunming Medical College, Kunming, Yunnan, China;(3) The Section of Cardiology, The Department of Medicine, Baylor College of Medicine, Houston, TX, USA |
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| Abstract: | ![]()
Purpose We assessed the ability of Aliskiren (AL), a direct renin inhibitor, and Valsartan (VA), an angiotensin receptor blocker, to limit myocardial infarct size (IS) in mice with type-2 diabetes mellitus. |
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