|
|||||
|
|
Theoretical development and critical analysis of burst frequency equations for passive valves on centrifugal microfluidic platforms |
|
| Authors: | Tzer Hwai Gilbert Thio Salar Soroori Fatimah Ibrahim Wisam Al-Faqheri Norhayati Soin Lawrence Kulinsky Marc Madou |
| Affiliation: | 1. Medical Informatics and Biological Micro-electro-mechanical Systems (MIMEMS) Specialized Laboratory, Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603, Kuala Lumpur, Malaysia 2. Department of Biomedical Engineering, University of California, Irvine, Irvine, 92697, USA 3. Department of Electrical Engineering, Faculty of Engineering, University of Malaya, 50603, Kuala Lumpur, Malaysia 4. Department of Mechanical and Aerospace Engineering, University of California, Irvine, Irvine, 92697, USA 5. Ulsan National Institute of Science and Technology (UNIST), World Class University (WCU), Ulsan, South Korea |
| Abstract: | This paper presents a theoretical development and critical analysis of the burst frequency equations for capillary valves on a microfluidic compact disc (CD) platform. This analysis includes background on passive capillary valves and the governing models/equations that have been developed to date. The implicit assumptions and limitations of these models are discussed. The fluid meniscus dynamics before bursting is broken up into a multi-stage model and a more accurate version of the burst frequency equation for the capillary valves is proposed. The modified equations are used to evaluate the effects of various CD design parameters such as the hydraulic diameter, the height to width aspect ratio, and the opening wedge angle of the channel on the burst pressure. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |