Cu/Zn superoxide dismutase expression in the postnatal rat brain following an excitotoxic injury |
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| Authors: | Peluffo Hugo Acarin Laia Faiz Maryam Castellano Bernardo Gonzalez Berta |
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| Affiliation: | (1) Unit of Histology, Department Of Cell Biology, Physiology, and Immunology, Autonomous University of Barcelona, 08193, Spain;(2) Institute of Neuroscience, Autonomous University of Barcelona, 08193, Spain |
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| Abstract: | ![]()
Background In the nervous system, as in other organs, Cu/Zn superoxide dismutase (Cu/Zn SOD) is a key antioxidant enzyme involved in superoxide detoxification in normal cellular metabolism and after cell injury. Although it has been suggested that immature brain has a different susceptibility to oxidative damage than adult brain, the distribution and cell-specific expression of this enzyme in immature brain and after postnatal brain damage has not been documented. |
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