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The expression of erythropoietin triggered by Danggui Buxue Tang, a Chinese herbal decoction prepared from Radix Astragali and Radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells
Authors:Ken Y.Z. Zheng  Heidi Q.H. Xie  Ava J.Y. Guo  Vicky P. Chen  Kevin Y. Zhu  Qiang Fu  Tina T.X. Dong  Karl W.K. Tsim
Affiliation:a Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China
b Beijing Friendship Hospital, Affiliate of Capital University of Medical Sciences, 95 Yong An Road, Beijing 100050, China
Abstract:
Keywords:DBT, Danggui Buxue Tang   RA, Radix Astragali   RAS, Radix Angelicae Sinensis   TCM, traditional Chinese medicine   EPO, erythropoietin   HRE, hypoxia response element   HIF, hypoxia-inducible factor   MAPK, mitogen-activated protein kinase   ERK, extracellular signal-regulated kinases   PEITC, phenethyl isothiocyanate   TPA, 12-O-tetra-decanoylphorbol 13-acetate
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