The expression of erythropoietin triggered by Danggui Buxue Tang, a Chinese herbal decoction prepared from Radix Astragali and Radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells |
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Authors: | Ken Y.Z. Zheng Heidi Q.H. Xie Ava J.Y. Guo Vicky P. Chen Kevin Y. Zhu Qiang Fu Tina T.X. Dong Karl W.K. Tsim |
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Affiliation: | a Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China b Beijing Friendship Hospital, Affiliate of Capital University of Medical Sciences, 95 Yong An Road, Beijing 100050, China |
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Abstract: | |
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Keywords: | DBT, Danggui Buxue Tang RA, Radix Astragali RAS, Radix Angelicae Sinensis TCM, traditional Chinese medicine EPO, erythropoietin HRE, hypoxia response element HIF, hypoxia-inducible factor MAPK, mitogen-activated protein kinase ERK, extracellular signal-regulated kinases PEITC, phenethyl isothiocyanate TPA, 12-O-tetra-decanoylphorbol 13-acetate |
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