| 地麻滴鼻液的制备及质量控制研究 |
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| 引用本文： | 李冰,肖小军. 地麻滴鼻液的制备及质量控制研究[J]. 解放军药学学报, 2007, 23(3): 221-223 |
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| 作者姓名： | 李冰 肖小军 |
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| 作者单位： | 安徽陆军预备役步兵师第二团,卫生队,安徽,安庆 246003;安徽陆军预备役步兵师第二团,卫生队,安徽,安庆 246003 |
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| 摘 要： | 目的 地麻滴鼻液的制备及质量控制.方法 采用高效液相色谱法和直接滴定法测定制剂中主药地塞米松磷酸钠和盐酸麻黄碱的含量.结果 地塞米松磷酸钠和盐酸麻黄碱平均回收率为99.92%、99.68%,RSD分别为1.21%和0.37%.结论 该滴鼻液制备工艺简单,质量可控,性质稳定,适合师医院和卫生队制剂.
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| 关 键 词： | 地塞米松磷酸钠 盐酸麻黄碱 滴鼻液 制备 质量控制 |
| 文章编号： | 1008-9926（2007）03-0221-03 |
| 修稿时间： | 2006-02-082006-11-17 |
Stndies on Preparation and Quality Control of Dexamethasone and Ephedrine Nasal Drops |
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| LI Bing,XIAO Xiao-Jun. Stndies on Preparation and Quality Control of Dexamethasone and Ephedrine Nasal Drops[J]. Pharmaceutical Journal of Chinese People's Liberation Army, 2007, 23(3): 221-223 |
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| Authors: | LI Bing XIAO Xiao-Jun |
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| Affiliation: | Department of Sanitation,The Anhui Reserve Army of PLA,Anqing 246003,Anhui China |
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| Abstract: | Aim To study the preparation of dexamethasone and ephedrine nasal drops and its quality control.Methods The method of determining dexamethasone sodium phosphate and ephedrine hydrochloride by HPLC and acid-base titration was used.Results The average recoveries of dexamethasone sodium phosphate and ephedrine hydrochloride were 99.92% and 99.68%,respectively.RSD was 1.21% and 0.37%,respectively.Conclusion This nasal drops can be easily prepared.The quality can be controlled and the property is stable.It's suitable for hospital preparation. |
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| Keywords: | Dexamethasone Sodium Phosphate Ephedrine Hydrochloride Nasaldrops Prepared Qualitycontroll |
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