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Life-threatening infantile diarrhea from fluoroquinolone-resistant Salmonella enterica typhimurium with mutations in both gyrA and parC |
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| Authors: | Nakaya Hideo Yasuhara Akihiro Yoshimura Ken Oshihoi Yukio Izumiya Hidemasa Watanabe Haruo |
| Affiliation: | Kansai Medical University Kohri Hospital, Osaka, Japan. nakaya@kouri.kmu.ac.jp |
| Abstract: | Salmonella Typhimurium DT12, isolated from a 35-day-old infant with diarrhea, was highly resistant to ampicillin, tetracycline, chloramphenicol, streptomycin, gentamycin, sulfamethoxazole/trimethoprim, nalidixic acid, and fluoroquinolones. The patient responded to antibiotic therapy with fosfomycin. Multidrug-resistance may become prevalent in Salmonella infections in Japan, as shown in this first case of a patient infected with fluoroquinolone-resistant Salmonella. |
| Keywords: | Salmonella Typhimurium mutation fluoroquinolone dispatch |
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