The role of dendritic cells in neurodegenerative diseases |
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| Authors: | Iribarren Pablo Cui You-Hong Le Yingying Wang Ji Ming |
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| Affiliation: | Laboratory of Molecular Immunoregulation, Center for Cancer Research, National Cancer Institute at Frederick, Building 560, Room 31-40, Frederick, MD 21702, USA. iribarrenp@mail.ncifcrf.gov |
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| Abstract: | ![]()
Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs) involved in the induction of adaptive immune responses. The presence of DCs in the central nervous system (CNS) and the active participation of the immune system in a variety of neurodegenerative diseases have been demonstrated. This review will discuss recent findings pertinent to DCs and other antigen-presenting cells in the CNS in health and disease states. |
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