The Association between Latrine Use and Trachoma: A Secondary Cohort Analysis from a Randomized Clinical Trial |
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| Authors: | Meron Haile Zerihun Tadesse Sintayehu Gebreselassie Berhan Ayele Teshome Gebre Sun N. Yu Nicole E. Stoller Bruce D. Gaynor Travis C. Porco Paul M. Emerson Thomas M. Lietman Jeremy D. Keenan |
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| Affiliation: | Francis I. Proctor Foundation, University of California, San Francisco, California; The Carter Center, Addis Ababa, Ethiopia; Departments of Ophthalmology and Epidemiology and Biostatistics, University of California, San Francisco, California; The Carter Center, Atlanta, Georgia; Institute for Global Health, University of California, San Francisco, California |
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| Abstract: | ![]()
Latrine use has been promoted as a component of an integrated strategy for trachoma control. As part of a randomized trial in Ethiopia, 12 communities received a mass azithromycin distribution followed by a latrine promotion intervention. A random sample of children ages 0–9 years in each community was monitored longitudinally for ocular chlamydia. After latrine construction ended, those communities with a higher proportion of households using latrines were more likely to experience a reduction in the prevalence of ocular chlamydia. Specifically, for each 10% increase in latrine use, there was a 2.0% decrease (95% confidence interval = 0.2–3.9% decrease) in the community prevalence of ocular chlamydia over the subsequent year (P = 0.04). |
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