慢阻肺急性加重期患者预后的影响因素分析

目的探讨慢性阻塞性肺病急性加重期(AECOPD)患者预后的相关危险因素。方法回顾性调查、收集58例AECOPD患者可能影响其预后的相关因素,并对其分别进行单因素分析。并进行Logistic多元逐步回归进行多因素分析,筛选影响AECOPD患者预后的独立危险因素。结果单因素分析后将结果 P0.1的因素纳入多因素Logistic回归,分析发现是否合并呼吸衰竭、气促程度、白细胞计数、APACHEⅡ、应用抗氧化剂、慢阻肺治疗依从性为影响AECOPD患者预后不佳的独立因素(P0.05)。结论根据AECOPD患者预后的独立危险因素,及早判断,选择合适的后续治疗方案,对提高其生存率及生存质量具有重要意义。

Analysis of influencing factors of prognosis of AECOPD patients

Objective To study the related risk factors of prognosis of patients with acute exacerbative chro-nic obstructive pulmonary disease ( AECOPD) . Methods The related factors might affect the prognosis of 58 AE-COPD patients were retrospectively collected, and then they were analyzed by single factor analysis and Logistic mult-ivariate stepwise regression. Results The single factor analysis and the multi-ariable Logistic regression analysis found that the risk factors included the combination of respiratory failure, serious shortness of breath, high white blood cell, high APACHE Ⅱ scores, application of antioxidants and bad treatment adherence (P<0. 05). Conclu-sion It has great significance to improve the survival rate and survival quality by choosing the appropriate treatment for AECOPD patients as early as possible.