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3D打印技术在制剂工艺中的研究进展与应用
引用本文:刘冬涵,梁军,罗菊元,刘彩凤,武慧超,杜守颖. 3D打印技术在制剂工艺中的研究进展与应用[J]. 中草药, 2019, 50(17): 4013-4019
作者姓名:刘冬涵  梁军  罗菊元  刘彩凤  武慧超  杜守颖
作者单位:北京中医药大学, 北京 100029,北京中医药大学, 北京 100029,北京中医药大学, 北京 100029,北京中医药大学, 北京 100029,北京中医药大学, 北京 100029,北京中医药大学, 北京 100029
基金项目:中央高校基本科研业务费专项资金资助项目(2017-JYB-JS-011)
摘    要:随着材料化学、计算机等高新技术的发展,制剂工艺也在不断创新与进步。近年来,3D打印技术成为制剂行业的研究热点。不同于传统制剂方法,3D打印技术可实现药物的个性化生产,解决药物存储问题,且由于其具有生产简单、携带方便、成本较低、患者依从性好等优势,在制剂领域具有良好的发展前景。通过检索CNKI、SCI、Springer数据库并整理相关文献,对3D打印的原理及其在制剂领域的最新研究进展、优势及挑战进行综述,并对3D打印技术在中药制剂领域的发展进行预测,旨在为该技术在中药制剂行业中的应用提供一定思路与参考。

关 键 词:3D打印技术  制剂工艺  个性化生产  中药制剂  高新技术
收稿时间:2019-02-26

Research progress and application of 3D printing technology in preparation process
LIU Dong-han,LIANG Jun,LUO Ju-yuan,LIU Cai-feng,WU Hui-chao and DU Shou-ying. Research progress and application of 3D printing technology in preparation process[J]. Chinese Traditional and Herbal Drugs, 2019, 50(17): 4013-4019
Authors:LIU Dong-han  LIANG Jun  LUO Ju-yuan  LIU Cai-feng  WU Hui-chao  DU Shou-ying
Affiliation:Beijing University of Chinese Medicine, Beijing 100029, China,Beijing University of Chinese Medicine, Beijing 100029, China,Beijing University of Chinese Medicine, Beijing 100029, China,Beijing University of Chinese Medicine, Beijing 100029, China,Beijing University of Chinese Medicine, Beijing 100029, China and Beijing University of Chinese Medicine, Beijing 100029, China
Abstract:With the development of high and new technology, such as material chemistry and computer technology, the formulation process is also constantly innovating and improving. In recent years, 3D printing technology has become a research hotspot in the formulation industry. Different from traditional preparation methods, 3D printing technology can realize personalized production and solve storage problems of drugs. Because of its advantages of simple production, convenient carrying, low cost and strong patient compliance, it may change the design and production mode of drugs in the future and have good development prospects in the field of preparation. This paper reviews principles, the latest research progresses, advantages and challenges of 3D printing by searching CNKI, SCI, Springer databases and collating relevant literatures, and forecasts the development of 3D printing technology in the field of traditional Chinese medicine preparations, aiming to provide some references for the application of the technology in the traditional Chinese medicine preparation industry.
Keywords:3D printing technology  preparation process  individuality production  Chinese materia medica preparation  high and new technology
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