菊花化学成分、药理作用的研究进展及质量标志物预测分析

菊花作为我国传统的一味中药材,种类繁多,分布广泛,具有很高的药用价值。菊花在药用和保健中都有很好的效果,是我国卫生部发布的第一批药食两用药材。近年来,菊花在药品及保健食品中的应用越来越广泛,其主要的药效成分为黄酮、挥发油和苯丙素类化合物。在对其化学成分及药理作用综述的基础上,结合质量标志物概念,基于化学成分、临床药效、药动学、传统药性、传统药效、不同储藏条件以及不同加工方法的影响等几个方面对菊花质量标志物进行预测分析,为菊花质量评价研究提供科学依据。

Research progress on chemical constituents and pharmacological effects of Chrysanthemum morifolium and predictive analysis on quality markers

As a kind of Chinese medicinal material, Chrysanthemum morifolium is numerous and widely distributed, which has high medicinal value. C. morifolium has a good effect in medicinal and health care, and it is also the first batch of being used for both medicine and food issued by Ministry of Health of China. In recent years, C. morifolium has been widely used in medicine and health foods. Flavonoids, volatile oils, and phenylpropanoids are its main effective components. Based on the review of its chemical composition and pharmacological effects, combined with the definition of Q-marker, this study processed predictive analysis on Q-marker of C. morifolium at aspects of chemical composition, clinical efficacy, pharmacokinetics, traditional medicinal properties, traditional pharmacodynamics, different storage conditions, and different processing methods, which can establish scientific quality standards of C. morifolium.