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氟哌啶醇治疗精神分裂症的增效作用
引用本文:王伟男,丛晓山,孙红杰,刘振英. 氟哌啶醇治疗精神分裂症的增效作用[J]. 临床精神医学杂志, 2009, 19(2)
作者姓名:王伟男  丛晓山  孙红杰  刘振英
作者单位:河北省荣军医院精神科,保定,071000;河北省荣军医院精神科,保定,071000;河北省荣军医院精神科,保定,071000;河北省荣军医院精神科,保定,071000
摘    要:目的:评价奎硫平合并氟哌啶醇治疗精神分裂症的疗效与不良反应。方法:对110例单纯口服奎硫平的精神分裂症患者疗效不佳者合并氟哌啶醇治疗12周。用阳性症状和阴性症状量表(PANSS)评定疗效,用UKU不良反应评定量表评定不良反应。结果:治疗12周末PANSS量表总分及各分量表评分较治疗前均有显著下降(P<0.05或P<0.01);有效率达71.82%;不良反应无明显增加(P>0.05)。结论:奎硫平合并氟哌啶醇治疗精神分裂症疗效肯定,不良反应较轻。

关 键 词:奎硫平  氟哌啶醇  精神分裂症

Study of quetiapine combined with haloperidol in the treatment of schizophrenia
WANG Wei-nan,CONG Xiao-shan,SUN Hong-jie,LI U Zhen-ying. Study of quetiapine combined with haloperidol in the treatment of schizophrenia[J]. Journal of Clinical Psychological Medicine, 2009, 19(2)
Authors:WANG Wei-nan  CONG Xiao-shan  SUN Hong-jie  LI U Zhen-ying
Affiliation:WANG Wei-nan,CONG Xiao-shan,SUN Hong-jie,LIU Zhen-ying.Rongjun Hospital of Hebei Province,Baoding 071000,China
Abstract:Objective: To evaluate the efficacy and adverse effects in patients with schizophrenia treated with quetiapine combined with haloperidol. Method:110 patients with schizophrenia,who had poorer efficacy treated with oral quetiapine,were treated with quetiapine plus haloperidol for 12 weeks.Efficacy and adverse effects were evaluated by Positive and Negative Syndrome Scale(PANSS)and Udvalg for Kliniske Undersogelser Side Effect Rating Scale(UKU),respectively. Results:The PANSS total scores and subscale scores ...
Keywords:quetiapine  haloperidol  schizophrenia  
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