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| 溶血尿毒综合征的诊治进展 | |
| 引用本文： | 刘小荣. 溶血尿毒综合征的诊治进展[J]. 中华肾病研究电子杂志, 2016, 5(2): 61-64. DOI: 10.3877/cma.j.issn.2095-3216.2016.02.004 |
| 作者姓名： | 刘小荣 |
| 作者单位： | 1. 100045 北京首都医科大学附属北京儿童医院肾病科、儿童慢性肾脏病及血液净化北京市重点实验室 |
| 基金项目： | 北京市科委首都特色(Z161100000516106) |
| 摘 要： | 溶血尿毒综合征(HUS)属于血栓性微血管性疾病。以微血管性溶血性贫血(可找到红细胞碎片)、血小板减少、肾功能损伤为特点。微血栓主要分布于肾脏。感染、多种毒素、抗内皮细胞抗体、药物等因素使内皮损伤是发病的关键。近年来随着对HUS的病因和发病机制有了新的认识，输注血浆和血浆置换是目前治疗HUS最有效的方法，已大大提高了HUS患者的生存率。 |
| 关 键 词： | 溶血尿毒综合征 儿童 诊断 治疗 |
| 收稿时间： | 2016-03-01 |
Progress in diagnosis and treatment of hemolytic uremic syndrome |
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| Xiaorong Liu. Progress in diagnosis and treatment of hemolytic uremic syndrome[J]. Chinese Journal of kidney disease investigation (Electronic Edition), 2016, 5(2): 61-64. DOI: 10.3877/cma.j.issn.2095-3216.2016.02.004 | |
| Authors: | Xiaorong Liu |
| Affiliation: | 1. Department of Nephrology, Beijing Children′s Hospital Affiliated to Capital University of Medical Sciences, Beijing Key Laboratory for Children′s Chronic Kidney Diseases and Blood Purification, Beijing 100045, China |
| Abstract: | Hemolytic uremic syndrome (HUS) is a thrombotic microvascular disease, characterized by microvascular hemolytic anemia (red blood cell debris can be found), thrombocytopenia, and renal function damage. Micro thrombus mainly distributed in the kidney. Key factors for the pathogenesis includes infection, toxins, anti-endothelial cell antibodies, and drugs. In recent years, new recognition has been made for the causes and pathogenesis of HUS, and plasma infusion and plasmapheresis have been the most effective methods for treatment of HUS, greatly improving the survival rate of HUS patients. |
| Keywords: | Hemolytic uremic syndrome Child Diagnosis Treatment |
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