胸段食管鳞癌患者的喉返神经旁淋巴结转移特点

目的探究胸段食管鳞癌患者的喉返神经旁淋巴结转移特点。 方法回顾性分析福建协和医院胸外科2012年1月至2015年12月间收治的行胸腹腔镜联合食管癌切除术的294例胸段食管鳞癌患者的喉返神经旁淋巴结清扫及转移情况，并分析喉返神经旁淋巴结转移特点。 结果294例行喉返神经旁淋巴结清扫的患者中，有88例患者有喉返神经旁淋巴结转移，转移率为29.93%；共清扫喉返神经旁淋巴结1 899枚，转移淋巴结145枚，转移度为7.64%。胸段食管鳞癌患者左、右喉返神经旁淋巴结转移与肿瘤浸润深度、分化程度、脉管瘤栓均有显著相关性(P<0.05)，但与性别、年龄、肿瘤部位无显著相关性(P>0.05)。 结论胸段食管鳞癌患者易发生喉返神经旁淋巴结转移。对于肿瘤浸润程度大、分化程度差、有脉管瘤栓的胸段食管鳞癌患者，应重视左、右两侧喉返神经旁淋巴结清扫。

Metastasis characteristics of lymph nodes of recurrent laryngeal nerve in patients with thoracic segment esophageal squamous cell carcinoma

ObjectiveTo investigate the metastasis characteristics of lymph nodes of recurrent laryngeal nerve in patients with thoracic segment esophageal squamous cell carcinoma. MethodsThe clinical data of the dissection and metastasis of lymph nodes of recurrent laryngeal nerve of 294 patients with thoracic segment esophageal squamous carcinoma undergoing esophageal carcinoma resection with thoracoscope and laparoscope in Fujian Medical University Union Hospital between January 2012 and December 2015 were retrospectively analyzed, and the metastasis characteristics of the lymph nodes of recurrent laryngeal nerve were investigated. ResultsAmong the 294 patients, 88 experienced metastasis of lymph nodes of recurrent laryngeal nerve, with the metastasis rate of 29.93%. A total of 1899 lymph nodes of recurrent laryngeal nerve were dissected, among which there were 145 metastatic lymph nodes, with the metastasis ratio of 7.64%. The metastasis of the lymph nodes of bilateral recurrent laryngeal nerve in patients with thoracic segment esophageal squamous cell carcinoma was significantly related to the depth of invasion, differentiated degree and carcinoma cell embolus(P<0.05), but was not significantly related to gender, age and tumor location(P>0.05). ConclusionsPatients with thoracic segment esophageal squamous cell carcinoma are susceptible to metastasis of lymph nodes of recurrent laryngeal nerve. To the patients with deeper invasion, poorer differentiation and having carcinoma cell embolus, special attention should be paid to the dissection of lymph nodes of bilateral recurrent laryngeal nerve.