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Long-term efficacy of plasma-derived hepatitis B vaccine among Chinese children: a 12-year follow-up study |
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| Authors: | Liao Su-Su Li Rong-Cheng Li Hui Yang Jin-Ye Zeng Xian-Jia Gong Jian Wang Shu-Sheng Li Yan-Ping Zhang Kong-Lai |
| Affiliation: | 1. Institute of Basic Medical Sciences, Peking Union Medical College and Chinese Academy of Medical Sciences 2. Provincial Anti-epidemic Station of Guangxi Autonomous Region |
| Abstract: | INTRODUCTION To evaluate long-term efficacy of a plasma-derived hepatitis B vaccine and provide evidence for decision-making on the vaccine booster doses, we conducted a prevalent follow-up study to examine serologic changes in hepatitis markers and vaccine efficacy in 350 children from the original cohort of 513 children who participated in a randomized, double-blind and placebo-controlled trial on a plasma-derived hepatitis B vaccine in Longan County, Guangxi Autonomous Region, China, in 1982. |
| Keywords: | Hepatitis B vaccines hepatitis B virus HBsAg follow-up study |
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