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Rheumatoid arthritis associated with ulcerative colitis
Authors:Yasushi Adachi  Yuji Hinoda  Hiroki Takahashi  Naoaki Nakagawa  Hirofumi Sakamoto  Fumio Itoh  Takao Endo  Sansyou Suzuki  Kohzoh Imai
Affiliation:(1) First Department of Internal Medicine, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, 060 Sapporo, Japan;(2) Department of Internal Medicine, Imagane Kokuho Hospital, 17-2 Imagane, Imagane-cho, 049-43 Setana, Hokkaido, Japan
Abstract:
This report describes a 58-year-old man with rheumatoid arthritis (RA) and interstitial pneumonia who suffered from low-grade fever, abdominal pain, and bloody diarrhea 16 months after the diagnosis of RA. Ulcerative colitis (UC) was diagnosed, based on endoscopic and histological findings. RA associated with UC is rare and the underlying mechanism is unknown. We discuss here whether vasculitis and HLA class may play some role in the association of RA with UC.
Keywords:ulcerative colitis  rheumatoid arthritis  vasculitis  HLA
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