Adipose derived stem cells and nerve regeneration |
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| Authors: | Alessandro Faroni, Richard JP Smith, Adam J Reid |
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| Affiliation: | [1]Blond Mclndoe Laboratories, Institute of Inflammation and Repair, University of Manchester, Manchester, UK; [2]Department of Plastic Surgery & Burns, University Hospital of South Manchester, Manchester, UK |
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| Abstract: | ![]()
Injuries to peripheral nerves are common and cause life-changing problems for patients alongside high social and health care costs for society. Current clinical treatment of peripheral nerve injuries predominantly relies on sacrificing a section of nerve from elsewhere in the body to provide a graft at the injury site. Much work has been done to develop a bioengineered nerve graft, precluding sacrifice of a functional nerve. Stem cells are prime candidates as accelerators of regeneration in these nerve grafts. This review examines the potential of adipose-derived stem cells to improve nerve repair assisted by bioengineered nerve grafts. |
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| Keywords: | peripheral nerve injury adipose derived stem cells nerve guidance tubes bioengineerednerve graft axonal regeneration Schwann cell cell therapy nerve repair |
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